DISPIRO TETRAOXANE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MALARIA AND/OR CANCER

A compound having the formula (I) wherein ring A represents a substituted or unsubstituted monocyclic or multicyclic ring; m=any positive integer; n=0-5; X=CH and Y=-C(O)NR 1 R 2 , -NR 1 R 2 or -S(O) 2 R 4 , where R 1 , R 2 and R 4 are each individually selected from the group consisting of H, subst...

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Bibliographische Detailangaben
Hauptverfasser: O'NEILL PAUL MICHAEL, WARD STEPHEN ANDREW, AMEWU RICHARD, ELLIS GEMMA, STACHULSKI ANDREW
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A compound having the formula (I) wherein ring A represents a substituted or unsubstituted monocyclic or multicyclic ring; m=any positive integer; n=0-5; X=CH and Y=-C(O)NR 1 R 2 , -NR 1 R 2 or -S(O) 2 R 4 , where R 1 , R 2 and R 4 are each individually selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted amine, substituted or unsubstituted carbocyclic ring, substituted or unsubstituted heterocyclic ring, or any combination thereof, or R 1 and R 2 are linked so as to form part of a substituted or unsubstituted heterocyclic ring; or X=N and Y=-S(O) 2 R 3 or -C(O)R 3 , where R 3 is selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted amine, substituted or unsubstituted carbocyclic ring, substituted or unsubstituted heterocyclic ring or any combination thereof.