Use of cyclopamine in the treatment of basal cell carcinoma and other tumors
The invention relates to a medicament for treatment of a patient having a tumor wherein Hedgehog/Smoothened signaling is utilized for prevention of apoptosis of tumor cells, comprising cyclopamine or another molecule that selectively inhibits Hedgehog/Smoothened signaling, wherein cyclopamine or sai...
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| creator | TAS, SINAN |
| description | The invention relates to a medicament for treatment of a patient having a tumor wherein Hedgehog/Smoothened signaling is utilized for prevention of apoptosis of tumor cells, comprising cyclopamine or another molecule that selectively inhibits Hedgehog/Smoothened signaling, wherein cyclopamine or said another molecule is in an amount adequate for a dosing that induces apoptosis of the tumor cells in the patient and causes decrease of size or disappearance of the tumor. |
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fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS ; STEROIDS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150107&DB=EPODOC&CC=EP&NR=2216022B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150107&DB=EPODOC&CC=EP&NR=2216022B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAS, SINAN</creatorcontrib><title>Use of cyclopamine in the treatment of basal cell carcinoma and other tumors</title><description>The invention relates to a medicament for treatment of a patient having a tumor wherein Hedgehog/Smoothened signaling is utilized for prevention of apoptosis of tumor cells, comprising cyclopamine or another molecule that selectively inhibits Hedgehog/Smoothened signaling, wherein cyclopamine or said another molecule is in an amount adequate for a dosing that induces apoptosis of the tumor cells in the patient and causes decrease of size or disappearance of the tumor.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNijEKAjEQRdNYiHqHuYDgRvAAyoqFhYXWyxj_YiCZCclYeHtX8AA27xXvzd351kA6UniHpIVzFFAUsifIKtgyxL79zo0TBaQJXEMUzUwsD9JprWSvrLUt3Wzk1LD6eeHo2F8PpzWKDmiFAwQ29Bfvu93G-323_WP5AO9CNOE</recordid><startdate>20150107</startdate><enddate>20150107</enddate><creator>TAS, SINAN</creator><scope>EVB</scope></search><sort><creationdate>20150107</creationdate><title>Use of cyclopamine in the treatment of basal cell carcinoma and other tumors</title><author>TAS, SINAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2216022B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; 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| language | eng ; fre ; ger |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS STEROIDS |
| title | Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
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