TSH RECEPTOR ANTAGONIZING TETRAHYDROQUINOLINE COMPOUNDS

The present invention relates the use of a compound, a pharmaceutical composition, compounds and a kit for treating or preventing disorders in a mammal responsive to TSH receptor mediated pathways, including disorders such as hyperthyroidism, Graves' disease, Graves Ophthalmopathy, Graves'...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PLATE, Ralf, VAN KOPPEN, Christianus, Johannes, TIMMERS, Cornelis, Marius, KARSTENS, Willem, Frederik, Johan, CONTI, Paolo, Giovanni, Martino
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates the use of a compound, a pharmaceutical composition, compounds and a kit for treating or preventing disorders in a mammal responsive to TSH receptor mediated pathways, including disorders such as hyperthyroidism, Graves' disease, Graves Ophthalmopathy, Graves' associated pretibial dermopathy, nodular goitre and thyroid cancer comprising administering to said mammal an effective amount of a tetrahydroquinoline compound of Formula (I) or an pharmaceutically acceptable salt thereof.