CELL-PENETRATING PEPTIDES AND USE THEREOF BONDED TO BIOMOLECULES WITH THERAPEUTIC ACTION

CELL-PENETRATING PEPTIDES AND USE THEREOF BONDED TO BIOMOLECULES WITH THERAPEUTIC ACTION

The present invention relates to use of a new cell penetrating peptides (CPP) and in particular to the region 32-51 of protein Limulus antilipopolisacirido (LALF) and its analogous. This invention refers to compositions containing these peptides associated to biomolecules with therapeutics propertie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TORRENS MADRAZO, ISIS, DEL CARMEN, GRANADILLO RODRIGUEZ, MILAID, GUERRA VALLESPI, MARIBEL, REYES ACOSTA, OSVALDO, ACEVEDO CASTRO, BORIS ERNESTO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The present invention relates to use of a new cell penetrating peptides (CPP) and in particular to the region 32-51 of protein Limulus antilipopolisacirido (LALF) and its analogous. This invention refers to compositions containing these peptides associated to biomolecules with therapeutics properties. This invention consist of compositions comprise the covalent fusion of biomolecules, between this human papillomavirus antigens (HPV) to these CPP for induce a potent immune cellular responses against HPV and HPV protein antigen-exhibiting cells including HPV-associated tumors. The referred compositions are applicable in the pharmaceutical industry as vaccine for therapeutic use in human.