QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS

QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS

The present invention provides novel Quercetin derivatives of formula (I) and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1 is hydrogen, benzyl or substituted benzyl; R2 is hydrogen, benzyl or substituted benzyl, linear or branched (C1-C6) alkyl, substituted alkyl, ar...

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Hauptverfasser: JAGGI, MANU, SINGH, ANU T, HIRPARA, VITTHALBHAI KETAN, AGGARWAL, PAWAN, AWASTHI, ANSHUMALI, JOSHI, NARENDRA SHRIRAM, VERMA, RITU
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator JAGGI, MANU
SINGH, ANU T
HIRPARA, VITTHALBHAI KETAN
AGGARWAL, PAWAN
AWASTHI, ANSHUMALI
JOSHI, NARENDRA SHRIRAM
VERMA, RITU
description The present invention provides novel Quercetin derivatives of formula (I) and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1 is hydrogen, benzyl or substituted benzyl; R2 is hydrogen, benzyl or substituted benzyl, linear or branched (C1-C6) alkyl, substituted alkyl, aryl, substituted aryl, heterocycle and substituted heterocycle, useful for treatment of various disorders including cancer, multi-drug resistant cancers, viral infections etc. The invention also provides a process for the preparation of compounds of formula (I) and pharmaceutical compositions comprising the same.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS
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