QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS

QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS

The present invention provides novel Quercetin derivatives of formula (I) and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1 is hydrogen, benzyl or substituted benzyl; R2 is hydrogen, benzyl or substituted benzyl, linear or branched (C1-C6) alkyl, substituted alkyl, ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JAGGI, MANU, SINGH, ANU T, HIRPARA, VITTHALBHAI KETAN, AGGARWAL, PAWAN, AWASTHI, ANSHUMALI, JOSHI, NARENDRA SHRIRAM, VERMA, RITU
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides novel Quercetin derivatives of formula (I) and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1 is hydrogen, benzyl or substituted benzyl; R2 is hydrogen, benzyl or substituted benzyl, linear or branched (C1-C6) alkyl, substituted alkyl, aryl, substituted aryl, heterocycle and substituted heterocycle, useful for treatment of various disorders including cancer, multi-drug resistant cancers, viral infections etc. The invention also provides a process for the preparation of compounds of formula (I) and pharmaceutical compositions comprising the same.