ANTI-HIV TABLET FORMULATIONS COMPRISING DARUNAVIR

An anti-HIV tablet formulation comprising a core containing 0.1 to 1.5% by weight (w/w) of colloidal silicon dioxide and 0.4 to 0.9% by weight (w/w) of a lubricant, the balance of the core comprising darunavir, a disintegrant and a filler comprising a spray-dried mixture of microcrystalline cellulos...

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Bibliographische Detailangaben
Hauptverfasser: SMANS, GUIDO, FRANCISCUS, JANS, EUGEEN, MARIA, JOZEF
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An anti-HIV tablet formulation comprising a core containing 0.1 to 1.5% by weight (w/w) of colloidal silicon dioxide and 0.4 to 0.9% by weight (w/w) of a lubricant, the balance of the core comprising darunavir, a disintegrant and a filler comprising a spray-dried mixture of microcrystalline cellulose and colloidal silicon dioxide, the core being optionally coated with a film coating.