METHODS AND COMPOSITIONS FOR PULMONARY ADMINISTRATION OF A TNFa INHIBITOR

The invention describes methods of pulmonary delivery of a TNFalpha inhibitor to a subject having a disorder in which TNFalpha is detrimental, such that the disorder is treated. Also included is a method of achieving systemic circulation of a TNFalpha inhibitor in a subject comprising administering...

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Bibliographische Detailangaben
Hauptverfasser: LI, LUKIU, BYRON, PETER, R, REILAND, THOMAS, L, NICHOLSON, KATHERINE, SHI, YI, SAKAGAMI, MASAHIRO
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention describes methods of pulmonary delivery of a TNFalpha inhibitor to a subject having a disorder in which TNFalpha is detrimental, such that the disorder is treated. Also included is a method of achieving systemic circulation of a TNFalpha inhibitor in a subject comprising administering the TNFalpha inhibitor to the central lung region or the peripheral lung region of the subject via inhalation, such that systemic circulation of the TNFalpha inhibitor is achieved.