PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.

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Bibliographische Detailangaben
Hauptverfasser: WYNN, Thomas, COSSROW, Jennifer, LANE, Benjamin, LITTKE, Adam, KUMARAVEL, Gnanasambandam, VESSELS, Jeffrey, JONES, John, Howard, RAIMUNDO, Brian, CHEN, Weirong, GUAN, Bing, POWELL, Noel, FRANKLIN, Lloyd, LUGOVSKOY, Alexey, PENG, Hairuo, TANAKA, Hiroko, XIN, Zhili
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.