OPTICAL DISCS FOR ANALYSING BIOMOLECULES

The present invention describes optical discs on which polymer molecules can be analyzed. There is a method for determining a plurality of characteristics of a target molecule, the target molecule being localized on an optical substrate comprising pits and lands, comprising the steps of: (i) carryin...

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Bibliographische Detailangaben
Hauptverfasser:	RUNDQUIST, JONAS, LIONE, RICHARD ANTHONY, HANNING, ANDERS, LONGMAN, ROBERT JAMES, BRYNJOLFFSSEN, JITKA, LEXOW, PREBEN
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE INFORMATION STORAGE INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORDCARRIER AND TRANSDUCER PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention describes optical discs on which polymer molecules can be analyzed. There is a method for determining a plurality of characteristics of a target molecule, the target molecule being localized on an optical substrate comprising pits and lands, comprising the steps of: (i) carrying out a series of reactions to interrogate different defined characteristics of the target molecule, wherein each of the reactions occurs in a distinct pit; (ii) treating the optical substrate to modify either those pits where a reaction has occurred, or alternatively, those pits where a reaction has not occurred, to alter the reflective characteristics of the pits; and (iii) measuring reflectivity within the pits, to thereby determine different characteristics of the target.