P.ariasi polypeptides, P.perniciosus polypeptides and methods of use

P.ariasi polypeptides, P.perniciosus polypeptides and methods of use

Substantially purified salivary P. ariasi and P. pemiciosus polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the P. ariasi and P. pemiciosus polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immun...

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Bibliographische Detailangaben
Hauptverfasser: KAMHAWI, SHADEN, MILWARD, FRANCIS, VALENZUELA, JESUS, G, RIBIERO, JOSE, M., C, BELKAID, YASMINE, AUDONNET, JEANRISTOPHE, FISCHER, LAURENT
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Beschreibung
Zusammenfassung:Substantially purified salivary P. ariasi and P. pemiciosus polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the P. ariasi and P. pemiciosus polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating or preventing Leishmaniasis are disclosed.