Use of PITX2 nucleic acids for the improved treatment of breast cell proliferative disorders

The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrin...

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Hauptverfasser: HOEFLER, HEINZ, SCHMITT, ARMIN, MARX, ALMUTH, MAIER, SABINE, HARBECK, NADIA, NIMMRICH, INKO, KOENIG, THOMAS, LOOK, MAXIME, P, RUJAN, TAMAS, SCHMITT, MANFRED, MARTENS, JOHN, MODEL, FABIAN, FOEKENS, JOHN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.