A NOVEL POTENTIOMETRIC CHOLESTEROL SENSOR FOR THE QUANTITATIVE ESTIMATION OF TOTAL CHOLESTEROL IN HUMAN BLOOD SERUM

The present invention provides a novel sensor for the estimation of total cholesterol in human blood serum using molecular imprint of cholesterol. Human blood serum contains 150-250 mg/dl cholesterol. The present invention provides a sensor device and a process for the fabrication of ISFET (Ion Sele...

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Hauptverfasser: JAYALAKSHMI, MANDAPATI, RAO, MANDAPATI, MOHAN, MADHAVENDRA, SUNKARA, SAKUNTHALA, JAIN, YOGENDRA, KUMAR, VANAJA, SUNKAM, KANTAM, MANNEPALLI, LAKSHMI, MARGARET, ISUKAPALLY, AHMAD, SHAMIM, KHANNA, VINOD, KUMAR, SEKHAR, CHANDRA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides a novel sensor for the estimation of total cholesterol in human blood serum using molecular imprint of cholesterol. Human blood serum contains 150-250 mg/dl cholesterol. The present invention provides a sensor device and a process for the fabrication of ISFET (Ion Selective Field Effect Transister) coated with molecular imprint of cholesterol on the SiO2+Si3N4 dielectric gate of the said electrode. The molecular imprint of cholesterol (MIPC) anchored in to a silica matrix sensing material is identified as a sensing material which has specific selectivity towards the cholesterol in presence of other organic constituents in human blood serum.