TIGHTER-BINDING C-PEPTIDE INHIBITORS OF HIV-1 ENTRY

TIGHTER-BINDING C-PEPTIDE INHIBITORS OF HIV-1 ENTRY

The invention provides compositions and methods for the treatment of HIV infection, inhibition against drug-resistant strains of HIV-1 and methods of enhancing the anti-HIV potency of peptide inhibitors against drug-resistant strains of HIV-1. In particular, oligomeric C-peptide inhibitors for inhib...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PAUL, SUPARNA, ROOT, MICHAEL, STEGER, H. KIRBY, KAHLE, KRISTEN
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention provides compositions and methods for the treatment of HIV infection, inhibition against drug-resistant strains of HIV-1 and methods of enhancing the anti-HIV potency of peptide inhibitors against drug-resistant strains of HIV-1. In particular, oligomeric C-peptide inhibitors for inhibiting HIV entry into host cells are disclosed.