OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE

OPHTHALMIC COMPOSITIONS WITH A DISUCCINATE

The invention is directed to an ophthalmic composition comprising a disuccinate of formula I or a corresponding salt thereof; wherein R1 is selected from hydrogen, alkyl or -C(O)alkyl, the alkyl having one to twelve carbons and optionally one or more oxygen atoms, A is a methylene group or an oxyalk...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: MACLEOD, STEVEN, K
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention is directed to an ophthalmic composition comprising a disuccinate of formula I or a corresponding salt thereof; wherein R1 is selected from hydrogen, alkyl or -C(O)alkyl, the alkyl having one to twelve carbons and optionally one or more oxygen atoms, A is a methylene group or an oxyalkylene group, and n is from 2 to 8. The ophthalmic composition also includes a cationic antimicrobial component and a tonicity agent, wherein the tonicity agent provides for an osmolality of the composition from 200 mOs/kg to 420 mOsm/kg.