THIOPHENE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS

The present invention relates to compounds represented by formula IA or pharmaceutically acceptable salts and solvates thereof which are useful for treating flaviviridae viral infections wherein R 1 is C 1-6 alkyl or C 3-6 cycloalkyl; X is M is R 5 is cyclohexyl which is unsubstituted or substituted...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KUMAR DAS, SANJOY, YANNOPOULOS, CONSTANTIN G, DENIS, REAL, FALARDEAU, GUY, VAILLANCOURT, LOUIS, CHAN CHUN KONG, LAVAL, POISSON, CARL
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds represented by formula IA or pharmaceutically acceptable salts and solvates thereof which are useful for treating flaviviridae viral infections wherein R 1 is C 1-6 alkyl or C 3-6 cycloalkyl; X is M is R 5 is cyclohexyl which is unsubstituted or substituted one or more times by R 13 ; R 6 is or cyclohexyl which is substituted in the 4 position by R 14 ; and Y, R 14a and R 14 are as defined herein.