PROCESSES FOR SYNTHESIZING QUATERNARY 4,5-EPOXY-MORPHINAN ANALOGS AND ISOLATING THEIR N-STEREOISOMERS

PROCESSES FOR SYNTHESIZING QUATERNARY 4,5-EPOXY-MORPHINAN ANALOGS AND ISOLATING THEIR N-STEREOISOMERS

Methods for the synthesis of 4,5-epoxy-morphinaniums using dimethyl formamide and resolution of the diastereomeric products by means of HPLC.

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Bibliographische Detailangaben
Hauptverfasser: PEREZ, JULIO, HAN, AMY QI, AVEY, ALFRED A
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Methods for the synthesis of 4,5-epoxy-morphinaniums using dimethyl formamide and resolution of the diastereomeric products by means of HPLC.