Heterocyclyl pyrimidines
Heterocyclyl-pyrimidine compounds (I) and their salts are new. Heterocyclyl-pyrimidine compounds of formula (I) and their salts are new. X : alkyl or phenyl (both optionally substituted), H, halo or CN; Z : alkoxy, alkylthio or alkylsulfonyl (all optionally substituted) or -N(R 1>)-R 2>; Y 1&g...
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| creator | MALSAM, OLGA DR SCHWARZ, HANS-GEORG DR FRANKEN, EVA-MARIA DR MUELLER, MICHAEL DR DAHMEN, PETER DR WIESE, WELF BURKHARD DR ARNOLD, CHRISTIAN DR VOERSTE, ARND DR WROBLOWSKY, HEINZ-JUERGEN DR |
| description | Heterocyclyl-pyrimidine compounds (I) and their salts are new. Heterocyclyl-pyrimidine compounds of formula (I) and their salts are new. X : alkyl or phenyl (both optionally substituted), H, halo or CN; Z : alkoxy, alkylthio or alkylsulfonyl (all optionally substituted) or -N(R 1>)-R 2>; Y 1>aryl, heterocyclyl, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, arylalkyl, amino, 1-8C alkoxy, 1-8C alkylthio, 6-10C aryloxy, 6-10C arylthio, heterocyclyloxy, 6-10C aryl-1-4C alkoxy, 6-10C aryl-1-4C alkylthio, heterocyclyl-(1-4C)-alkoxy or heterocyclyl-(1-4C)-alkylthio (all optionally substituted) or halo; A : 3-10 membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle containing up to 4 heteroatom comprising O, N or S (optionally substituted by 1-3 R1d); R1d : halo, OH, CN, oxo, nitro, amino, mercapto, 1-6C alkyl, 1-6C haloalkyl, 2-6C alkenyl, 2-6C alkynyl, 3-6C cycloalkyl, 1-6C alkoxy, 1-6C haloalkoxy, 1-7C alkylcarbonylamino, 1-6C alkylamino, di-(1-6C alkyl)amino, 1-6C alkylthio, 1-6C alkylsulfinyl, 1-6C alkylsulfonyl, aminosulfonyl, 1-6C alkylaminosulfonyl or di-(1-6C alkyl)aminosulfonyl; W 1>-N(R 4>)-R 5>or (-N ->-R 5>)(M 1>); either R 1>H, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, heterocyclyl, OH, alkoxy, amine, alkylamine, dialkylamine, hydroxyalkyl, alkylcarbonyloxyalkyl or alkyloxycarbonyloxyalkyl; and R 2>H or alkyl; or NR 1>R 2>heterocyclic ring (optionally substituted); R 4>alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heteroaryl, arylalkyl, heteroarylalkyl or optionally saturated heterocyclyl (all optionally substituted) or H; M 1>cation; R 5>saturated, partially or completely unsaturated or aromatic, optionally substituted 5- or 6-ring heterocyclyl (containing one or up to three further heteroatom comprising N, S and\or O atom, where O atom may not be adjacent), COR 7>, S(O) 1 - 2R 7>, CN, COOR 7>, CON(R 7>)-R 8>, P(=L)(R 9>)-R 1> 0>or CON=S(R 1> 1>)-(R 1> 2>); L : O or S; either R 7>H, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl-alkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl; and R 8>alkyl, alkenyl, alkynyl or alkoxy (optionally substituted), H or NH-R 4>; or NR 7>R 8>optionally substituted and saturated ring (optionally interrupted by further heteroatom); either R 9>, R 1> 0>optionally substituted alkyl, alkenyl, alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, cycloalkenyloxy, cycloalkylalkoxy, alkylthio, alkenylthio, phenoxy, phenylthio, benzyloxy, benzylthio, heteroaryloxy, het |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP2092824A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP2092824A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP2092824A13</originalsourceid><addsrcrecordid>eNrjZJDwSC1JLcpPrkzOqcxRKKgsyszNTMnMSy3mYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgFGBpZGFkYmjobGRCgBAOT4ImE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Heterocyclyl pyrimidines</title><source>esp@cenet</source><creator>MALSAM, OLGA DR ; SCHWARZ, HANS-GEORG DR ; FRANKEN, EVA-MARIA DR ; MUELLER, MICHAEL DR ; DAHMEN, PETER DR ; WIESE, WELF BURKHARD DR ; ARNOLD, CHRISTIAN DR ; VOERSTE, ARND DR ; WROBLOWSKY, HEINZ-JUERGEN DR</creator><creatorcontrib>MALSAM, OLGA DR ; SCHWARZ, HANS-GEORG DR ; FRANKEN, EVA-MARIA DR ; MUELLER, MICHAEL DR ; DAHMEN, PETER DR ; WIESE, WELF BURKHARD DR ; ARNOLD, CHRISTIAN DR ; VOERSTE, ARND DR ; WROBLOWSKY, HEINZ-JUERGEN DR</creatorcontrib><description>Heterocyclyl-pyrimidine compounds (I) and their salts are new. Heterocyclyl-pyrimidine compounds of formula (I) and their salts are new. X : alkyl or phenyl (both optionally substituted), H, halo or CN; Z : alkoxy, alkylthio or alkylsulfonyl (all optionally substituted) or -N(R 1>)-R 2>; Y 1>aryl, heterocyclyl, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, arylalkyl, amino, 1-8C alkoxy, 1-8C alkylthio, 6-10C aryloxy, 6-10C arylthio, heterocyclyloxy, 6-10C aryl-1-4C alkoxy, 6-10C aryl-1-4C alkylthio, heterocyclyl-(1-4C)-alkoxy or heterocyclyl-(1-4C)-alkylthio (all optionally substituted) or halo; A : 3-10 membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle containing up to 4 heteroatom comprising O, N or S (optionally substituted by 1-3 R1d); R1d : halo, OH, CN, oxo, nitro, amino, mercapto, 1-6C alkyl, 1-6C haloalkyl, 2-6C alkenyl, 2-6C alkynyl, 3-6C cycloalkyl, 1-6C alkoxy, 1-6C haloalkoxy, 1-7C alkylcarbonylamino, 1-6C alkylamino, di-(1-6C alkyl)amino, 1-6C alkylthio, 1-6C alkylsulfinyl, 1-6C alkylsulfonyl, aminosulfonyl, 1-6C alkylaminosulfonyl or di-(1-6C alkyl)aminosulfonyl; W 1>-N(R 4>)-R 5>or (-N ->-R 5>)(M 1>); either R 1>H, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, heterocyclyl, OH, alkoxy, amine, alkylamine, dialkylamine, hydroxyalkyl, alkylcarbonyloxyalkyl or alkyloxycarbonyloxyalkyl; and R 2>H or alkyl; or NR 1>R 2>heterocyclic ring (optionally substituted); R 4>alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heteroaryl, arylalkyl, heteroarylalkyl or optionally saturated heterocyclyl (all optionally substituted) or H; M 1>cation; R 5>saturated, partially or completely unsaturated or aromatic, optionally substituted 5- or 6-ring heterocyclyl (containing one or up to three further heteroatom comprising N, S and\or O atom, where O atom may not be adjacent), COR 7>, S(O) 1 - 2R 7>, CN, COOR 7>, CON(R 7>)-R 8>, P(=L)(R 9>)-R 1> 0>or CON=S(R 1> 1>)-(R 1> 2>); L : O or S; either R 7>H, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl-alkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl; and R 8>alkyl, alkenyl, alkynyl or alkoxy (optionally substituted), H or NH-R 4>; or NR 7>R 8>optionally substituted and saturated ring (optionally interrupted by further heteroatom); either R 9>, R 1> 0>optionally substituted alkyl, alkenyl, alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, cycloalkenyloxy, cycloalkylalkoxy, alkylthio, alkenylthio, phenoxy, phenylthio, benzyloxy, benzylthio, heteroaryloxy, heteroarylthio, heteroarylalkoxy or heteroarylalkylthio; or PR 9>R 1> 0>optionally substituted 5-7-membered cycle that can be interrupted by one or two O and/or S; and R 1> 1>, R 1> 2>optionally substituted alkyl, alkenyl, alkynyl, phenyl or phenylalkyl. Independent claims are included for: (1) the preparation of (I); (2) acid substituted pyrimidine compounds of formula (V); and (3) an agent for combating animal pests and/or plant pathogenic fungal damage in and/or on plants or in and/or on seeds of plants, comprising: either (I) or their salts, and an auxiliary material and/or additives; or (I) or their salts and at least one ammonium or phosphonium salt of formula ([R 2> 9>-Q +>(R 2> 6>)(R 2> 8>)-R 2> 7>] nR 3> 0>(n ->)). Q : N or P; R 2> 6>-R 2> 9>1-8C alkyl or one or more times unsaturated 1-8C alkylene (both optionally substituted by halo, nitro or CN) or H; n : 1-4; and R 3> 0>inorganic or organic anion. [Image] [Image] ACTIVITY : Fungicide; Pesticide; Insecticide; Arachnicide; Antihelmintic; Nematocide; Acaricide; Antibacterial; Virucide; Antiparasitic; Antifouling; Cytostatic. MECHANISM OF ACTION : None given.
Die vorliegende Erfindung betrifft Heterocyclyl-Pyrimidine der nachfolgenden Formel (I)
ein Verfahren zur deren Herstellung, die Verwendung der erfindungsgemäßen Heterocyclyl-Pyrimidine zum Bekämpfen von tierischen Schädlingen und/oder pflanzenpathogenen Schadpilzen, Verfahren und Mittel zur Bekämpfung von tierischen Schädlingen und/oder pflanzenpathogenen Schadpilzen in und/oder auf Pflanzen oder in und/oder auf Saatgut von Pflanzen, Verfahren zur Herstellung solcher Mittel und behandeltes Saatgut sowie deren Verwendung zur Bekämpfung von Schädlingen und/oder pflanzenpathogenen Schadpilzen in der Land-, Garten- und Forstwirtschaft, in der Tiergesundheit, im Materialschutz sowie im Bereich Haushalt und Hygiene.</description><language>eng ; fre ; ger</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; FISHING ; FORESTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HUNTING ; METALLURGY ; ORGANIC CHEMISTRY ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; TRAPPING</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090826&DB=EPODOC&CC=EP&NR=2092824A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090826&DB=EPODOC&CC=EP&NR=2092824A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MALSAM, OLGA DR</creatorcontrib><creatorcontrib>SCHWARZ, HANS-GEORG DR</creatorcontrib><creatorcontrib>FRANKEN, EVA-MARIA DR</creatorcontrib><creatorcontrib>MUELLER, MICHAEL DR</creatorcontrib><creatorcontrib>DAHMEN, PETER DR</creatorcontrib><creatorcontrib>WIESE, WELF BURKHARD DR</creatorcontrib><creatorcontrib>ARNOLD, CHRISTIAN DR</creatorcontrib><creatorcontrib>VOERSTE, ARND DR</creatorcontrib><creatorcontrib>WROBLOWSKY, HEINZ-JUERGEN DR</creatorcontrib><title>Heterocyclyl pyrimidines</title><description>Heterocyclyl-pyrimidine compounds (I) and their salts are new. Heterocyclyl-pyrimidine compounds of formula (I) and their salts are new. X : alkyl or phenyl (both optionally substituted), H, halo or CN; Z : alkoxy, alkylthio or alkylsulfonyl (all optionally substituted) or -N(R 1>)-R 2>; Y 1>aryl, heterocyclyl, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, arylalkyl, amino, 1-8C alkoxy, 1-8C alkylthio, 6-10C aryloxy, 6-10C arylthio, heterocyclyloxy, 6-10C aryl-1-4C alkoxy, 6-10C aryl-1-4C alkylthio, heterocyclyl-(1-4C)-alkoxy or heterocyclyl-(1-4C)-alkylthio (all optionally substituted) or halo; A : 3-10 membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle containing up to 4 heteroatom comprising O, N or S (optionally substituted by 1-3 R1d); R1d : halo, OH, CN, oxo, nitro, amino, mercapto, 1-6C alkyl, 1-6C haloalkyl, 2-6C alkenyl, 2-6C alkynyl, 3-6C cycloalkyl, 1-6C alkoxy, 1-6C haloalkoxy, 1-7C alkylcarbonylamino, 1-6C alkylamino, di-(1-6C alkyl)amino, 1-6C alkylthio, 1-6C alkylsulfinyl, 1-6C alkylsulfonyl, aminosulfonyl, 1-6C alkylaminosulfonyl or di-(1-6C alkyl)aminosulfonyl; W 1>-N(R 4>)-R 5>or (-N ->-R 5>)(M 1>); either R 1>H, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, heterocyclyl, OH, alkoxy, amine, alkylamine, dialkylamine, hydroxyalkyl, alkylcarbonyloxyalkyl or alkyloxycarbonyloxyalkyl; and R 2>H or alkyl; or NR 1>R 2>heterocyclic ring (optionally substituted); R 4>alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heteroaryl, arylalkyl, heteroarylalkyl or optionally saturated heterocyclyl (all optionally substituted) or H; M 1>cation; R 5>saturated, partially or completely unsaturated or aromatic, optionally substituted 5- or 6-ring heterocyclyl (containing one or up to three further heteroatom comprising N, S and\or O atom, where O atom may not be adjacent), COR 7>, S(O) 1 - 2R 7>, CN, COOR 7>, CON(R 7>)-R 8>, P(=L)(R 9>)-R 1> 0>or CON=S(R 1> 1>)-(R 1> 2>); L : O or S; either R 7>H, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl-alkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl; and R 8>alkyl, alkenyl, alkynyl or alkoxy (optionally substituted), H or NH-R 4>; or NR 7>R 8>optionally substituted and saturated ring (optionally interrupted by further heteroatom); either R 9>, R 1> 0>optionally substituted alkyl, alkenyl, alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, cycloalkenyloxy, cycloalkylalkoxy, alkylthio, alkenylthio, phenoxy, phenylthio, benzyloxy, benzylthio, heteroaryloxy, heteroarylthio, heteroarylalkoxy or heteroarylalkylthio; or PR 9>R 1> 0>optionally substituted 5-7-membered cycle that can be interrupted by one or two O and/or S; and R 1> 1>, R 1> 2>optionally substituted alkyl, alkenyl, alkynyl, phenyl or phenylalkyl. Independent claims are included for: (1) the preparation of (I); (2) acid substituted pyrimidine compounds of formula (V); and (3) an agent for combating animal pests and/or plant pathogenic fungal damage in and/or on plants or in and/or on seeds of plants, comprising: either (I) or their salts, and an auxiliary material and/or additives; or (I) or their salts and at least one ammonium or phosphonium salt of formula ([R 2> 9>-Q +>(R 2> 6>)(R 2> 8>)-R 2> 7>] nR 3> 0>(n ->)). Q : N or P; R 2> 6>-R 2> 9>1-8C alkyl or one or more times unsaturated 1-8C alkylene (both optionally substituted by halo, nitro or CN) or H; n : 1-4; and R 3> 0>inorganic or organic anion. [Image] [Image] ACTIVITY : Fungicide; Pesticide; Insecticide; Arachnicide; Antihelmintic; Nematocide; Acaricide; Antibacterial; Virucide; Antiparasitic; Antifouling; Cytostatic. MECHANISM OF ACTION : None given.
Die vorliegende Erfindung betrifft Heterocyclyl-Pyrimidine der nachfolgenden Formel (I)
ein Verfahren zur deren Herstellung, die Verwendung der erfindungsgemäßen Heterocyclyl-Pyrimidine zum Bekämpfen von tierischen Schädlingen und/oder pflanzenpathogenen Schadpilzen, Verfahren und Mittel zur Bekämpfung von tierischen Schädlingen und/oder pflanzenpathogenen Schadpilzen in und/oder auf Pflanzen oder in und/oder auf Saatgut von Pflanzen, Verfahren zur Herstellung solcher Mittel und behandeltes Saatgut sowie deren Verwendung zur Bekämpfung von Schädlingen und/oder pflanzenpathogenen Schadpilzen in der Land-, Garten- und Forstwirtschaft, in der Tiergesundheit, im Materialschutz sowie im Bereich Haushalt und Hygiene.</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>CHEMISTRY</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>TRAPPING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJDwSC1JLcpPrkzOqcxRKKgsyszNTMnMSy3mYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgFGBpZGFkYmjobGRCgBAOT4ImE</recordid><startdate>20090826</startdate><enddate>20090826</enddate><creator>MALSAM, OLGA DR</creator><creator>SCHWARZ, HANS-GEORG DR</creator><creator>FRANKEN, EVA-MARIA DR</creator><creator>MUELLER, MICHAEL DR</creator><creator>DAHMEN, PETER DR</creator><creator>WIESE, WELF BURKHARD DR</creator><creator>ARNOLD, CHRISTIAN DR</creator><creator>VOERSTE, ARND DR</creator><creator>WROBLOWSKY, HEINZ-JUERGEN DR</creator><scope>EVB</scope></search><sort><creationdate>20090826</creationdate><title>Heterocyclyl pyrimidines</title><author>MALSAM, OLGA DR ; SCHWARZ, HANS-GEORG DR ; FRANKEN, EVA-MARIA DR ; MUELLER, MICHAEL DR ; DAHMEN, PETER DR ; WIESE, WELF BURKHARD DR ; ARNOLD, CHRISTIAN DR ; VOERSTE, ARND DR ; WROBLOWSKY, HEINZ-JUERGEN DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2092824A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2009</creationdate><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>CHEMISTRY</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>TRAPPING</topic><toplevel>online_resources</toplevel><creatorcontrib>MALSAM, OLGA DR</creatorcontrib><creatorcontrib>SCHWARZ, HANS-GEORG DR</creatorcontrib><creatorcontrib>FRANKEN, EVA-MARIA DR</creatorcontrib><creatorcontrib>MUELLER, MICHAEL DR</creatorcontrib><creatorcontrib>DAHMEN, PETER DR</creatorcontrib><creatorcontrib>WIESE, WELF BURKHARD DR</creatorcontrib><creatorcontrib>ARNOLD, CHRISTIAN DR</creatorcontrib><creatorcontrib>VOERSTE, ARND DR</creatorcontrib><creatorcontrib>WROBLOWSKY, HEINZ-JUERGEN DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MALSAM, OLGA DR</au><au>SCHWARZ, HANS-GEORG DR</au><au>FRANKEN, EVA-MARIA DR</au><au>MUELLER, MICHAEL DR</au><au>DAHMEN, PETER DR</au><au>WIESE, WELF BURKHARD DR</au><au>ARNOLD, CHRISTIAN DR</au><au>VOERSTE, ARND DR</au><au>WROBLOWSKY, HEINZ-JUERGEN DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Heterocyclyl pyrimidines</title><date>2009-08-26</date><risdate>2009</risdate><abstract>Heterocyclyl-pyrimidine compounds (I) and their salts are new. Heterocyclyl-pyrimidine compounds of formula (I) and their salts are new. X : alkyl or phenyl (both optionally substituted), H, halo or CN; Z : alkoxy, alkylthio or alkylsulfonyl (all optionally substituted) or -N(R 1>)-R 2>; Y 1>aryl, heterocyclyl, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, arylalkyl, amino, 1-8C alkoxy, 1-8C alkylthio, 6-10C aryloxy, 6-10C arylthio, heterocyclyloxy, 6-10C aryl-1-4C alkoxy, 6-10C aryl-1-4C alkylthio, heterocyclyl-(1-4C)-alkoxy or heterocyclyl-(1-4C)-alkylthio (all optionally substituted) or halo; A : 3-10 membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle containing up to 4 heteroatom comprising O, N or S (optionally substituted by 1-3 R1d); R1d : halo, OH, CN, oxo, nitro, amino, mercapto, 1-6C alkyl, 1-6C haloalkyl, 2-6C alkenyl, 2-6C alkynyl, 3-6C cycloalkyl, 1-6C alkoxy, 1-6C haloalkoxy, 1-7C alkylcarbonylamino, 1-6C alkylamino, di-(1-6C alkyl)amino, 1-6C alkylthio, 1-6C alkylsulfinyl, 1-6C alkylsulfonyl, aminosulfonyl, 1-6C alkylaminosulfonyl or di-(1-6C alkyl)aminosulfonyl; W 1>-N(R 4>)-R 5>or (-N ->-R 5>)(M 1>); either R 1>H, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, heterocyclyl, OH, alkoxy, amine, alkylamine, dialkylamine, hydroxyalkyl, alkylcarbonyloxyalkyl or alkyloxycarbonyloxyalkyl; and R 2>H or alkyl; or NR 1>R 2>heterocyclic ring (optionally substituted); R 4>alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heteroaryl, arylalkyl, heteroarylalkyl or optionally saturated heterocyclyl (all optionally substituted) or H; M 1>cation; R 5>saturated, partially or completely unsaturated or aromatic, optionally substituted 5- or 6-ring heterocyclyl (containing one or up to three further heteroatom comprising N, S and\or O atom, where O atom may not be adjacent), COR 7>, S(O) 1 - 2R 7>, CN, COOR 7>, CON(R 7>)-R 8>, P(=L)(R 9>)-R 1> 0>or CON=S(R 1> 1>)-(R 1> 2>); L : O or S; either R 7>H, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl-alkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl; and R 8>alkyl, alkenyl, alkynyl or alkoxy (optionally substituted), H or NH-R 4>; or NR 7>R 8>optionally substituted and saturated ring (optionally interrupted by further heteroatom); either R 9>, R 1> 0>optionally substituted alkyl, alkenyl, alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, cycloalkenyloxy, cycloalkylalkoxy, alkylthio, alkenylthio, phenoxy, phenylthio, benzyloxy, benzylthio, heteroaryloxy, heteroarylthio, heteroarylalkoxy or heteroarylalkylthio; or PR 9>R 1> 0>optionally substituted 5-7-membered cycle that can be interrupted by one or two O and/or S; and R 1> 1>, R 1> 2>optionally substituted alkyl, alkenyl, alkynyl, phenyl or phenylalkyl. Independent claims are included for: (1) the preparation of (I); (2) acid substituted pyrimidine compounds of formula (V); and (3) an agent for combating animal pests and/or plant pathogenic fungal damage in and/or on plants or in and/or on seeds of plants, comprising: either (I) or their salts, and an auxiliary material and/or additives; or (I) or their salts and at least one ammonium or phosphonium salt of formula ([R 2> 9>-Q +>(R 2> 6>)(R 2> 8>)-R 2> 7>] nR 3> 0>(n ->)). Q : N or P; R 2> 6>-R 2> 9>1-8C alkyl or one or more times unsaturated 1-8C alkylene (both optionally substituted by halo, nitro or CN) or H; n : 1-4; and R 3> 0>inorganic or organic anion. [Image] [Image] ACTIVITY : Fungicide; Pesticide; Insecticide; Arachnicide; Antihelmintic; Nematocide; Acaricide; Antibacterial; Virucide; Antiparasitic; Antifouling; Cytostatic. MECHANISM OF ACTION : None given.
Die vorliegende Erfindung betrifft Heterocyclyl-Pyrimidine der nachfolgenden Formel (I)
ein Verfahren zur deren Herstellung, die Verwendung der erfindungsgemäßen Heterocyclyl-Pyrimidine zum Bekämpfen von tierischen Schädlingen und/oder pflanzenpathogenen Schadpilzen, Verfahren und Mittel zur Bekämpfung von tierischen Schädlingen und/oder pflanzenpathogenen Schadpilzen in und/oder auf Pflanzen oder in und/oder auf Saatgut von Pflanzen, Verfahren zur Herstellung solcher Mittel und behandeltes Saatgut sowie deren Verwendung zur Bekämpfung von Schädlingen und/oder pflanzenpathogenen Schadpilzen in der Land-, Garten- und Forstwirtschaft, in der Tiergesundheit, im Materialschutz sowie im Bereich Haushalt und Hygiene.</abstract><oa>free_for_read</oa></addata></record> |
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| recordid | cdi_epo_espacenet_EP2092824A1 |
| source | esp@cenet |
| subjects | AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING |
| title | Heterocyclyl pyrimidines |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T12%3A36%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MALSAM,%20OLGA%20DR&rft.date=2009-08-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP2092824A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |