DENGUE DIAGNOSIS AND TREATMENT

We describe a method of providing an indication useful in the diagnosis or prognosis of dengue, the method comprising detecting a change in the expression pattern or level of: (a) a ubiquitin-proteasome pathway protein; (b) a interferon-related protein; or (c) an NF- B-mediated cytokine/chemokine re...

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Bibliographische Detailangaben
Hauptverfasser: HIBBERD, MARTIN, LLOYD, GU, FENG, TOLFVENSTAM, THOMAS, FINK, JOSHUA, VASUDEVAN, SUBHASH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:We describe a method of providing an indication useful in the diagnosis or prognosis of dengue, the method comprising detecting a change in the expression pattern or level of: (a) a ubiquitin-proteasome pathway protein; (b) a interferon-related protein; or (c) an NF- B-mediated cytokine/chemokine response protein. We also describe a method of identifying a molecule suitable for the treatment or prevention of dengue, the method comprising determining if a candidate molecule is an agonist or antagonist of any one or more of these proteins.