The use of enzymatic resolution for the preparation of intermediates of pregabalin

Provided is the use of enzymatic resolution for the preparation of intermediates of prcgabalin, including (3S)-cyano-5-methylhcxanoic acid and salts thereof and R-(-)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof.

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Bibliographische Detailangaben
Hauptverfasser: FISHMAN, AYELET, HEDVATI, LILACH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided is the use of enzymatic resolution for the preparation of intermediates of prcgabalin, including (3S)-cyano-5-methylhcxanoic acid and salts thereof and R-(-)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof.