PROTEASE INHIBITORS

The present invention provides HIV protease inhibitors of formulas I, IA, IB, Ib or II, or pharmaceutically acceptable salts thereof, wherein R2 may be, for example, 2-pyridyl-CH2-, 3-pyridyl-CH2-, 4-pyridyl-CH2-, a sulfonyl group as described in the formulas herein including benzenesulfonyl or thio...

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Bibliographische Detailangaben
Hauptverfasser: PANCHAL, CHANDRA J, LAVALLEE, JEAN-FRANCOIS, PERRON, VALERIE, MILOT, GUY, LEBERRE, NICOLAS, STRANIX, BRENT RICHARD, HERBART, DOMINIK
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides HIV protease inhibitors of formulas I, IA, IB, Ib or II, or pharmaceutically acceptable salts thereof, wherein R2 may be, for example, 2-pyridyl-CH2-, 3-pyridyl-CH2-, 4-pyridyl-CH2-, a sulfonyl group as described in the formulas herein including benzenesulfonyl or thiophenesulfonyl groups, R2a-CO)-, R2a being selected from the group consisting of piperonyl, 2-pyranzinyl (unsubstituted or substituted with H, or an alkyl of 1 to 4 carbon atoms) or a picolylamine group as described herein, wherein R3 may be, for example, a phenyl group or diphenylmethyl group as described herein, and wherein Cx may be, for example, COOH, CONR5R6, CH2OH or CH2OR7.