SUBSTITUTED PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE

SUBSTITUTED PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE

Substituted pyrazolopyrimidine derivatives of formula (I) wherein R 1 represents chloro or bromo, R 2 to R7 represent e.g. hydrogen, methyl or ethyl; and R 10 and R 11 independently represent e.g. hydrogen or C 1 -C 6 alkyl, are potent mGluR5 modulators and are useful for the prevention of acute and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FOTINS, JURIS, PARSONS, CHRISTOPHER GRAHAM RAPHAEL, WEIL, TANJA, MÜLLER, SYBILLE, JATZKE, CLAUDIA, KAULINA, LARISA, HECHENBERGER, MIRKO, GUTCAITS, ALEKSANDRS, KAUSS, VALERJANS, HENRICH, MARKUS, DANYSZ, WOJCIECH, DEKUNDY, ANDRZEJ, ZEMRIBO, RONALDS, ERDMANE, ELINA, NAGEL, JENS
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Substituted pyrazolopyrimidine derivatives of formula (I) wherein R 1 represents chloro or bromo, R 2 to R7 represent e.g. hydrogen, methyl or ethyl; and R 10 and R 11 independently represent e.g. hydrogen or C 1 -C 6 alkyl, are potent mGluR5 modulators and are useful for the prevention of acute and chronic neurological disorders.