Method employing GAPDH as molecular markers for cancer prognosis

The invention is predicated on the finding that the gene expression level of two genes, GAPDH and RPL37A, already exhibits a powerful predictive power for assessing the outcome of a neoplastic or cancerous disease. The invention relates to a method for predicting an outcome of a patient suffering fr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	WIRTZ, RALPH, VON TOERNE, CHRISTIAN, STROPP, UDO
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention is predicated on the finding that the gene expression level of two genes, GAPDH and RPL37A, already exhibits a powerful predictive power for assessing the outcome of a neoplastic or cancerous disease. The invention relates to a method for predicting an outcome of a patient suffering from or at risk of developing a neoplastic disease, said method comprising the steps of: a)obtaining a biological sample from said patient; b)quantifiably determining the gene expression level of GAPDH or RPL37A and at least one further housekeeping gene, wherein the expression level of GAPDH or RPL37A is determined in relation to the expression level of the at least one further housekeeping gene; c)arriving at a prediction by means of a mathematical discriminate function.