PROCESS FOR THE CRYSTALLISATION OF CEFADROXIL
The present invention relates to a process for the preparation of cefadroxil in crystal form, comprising: a) adding an aqueous solution of cefadroxil to a crystallisation vessel and a titrant to keep a pH in the crystallisation vessel of between 7 to 9; and b) lowering the pH in the crystallisation...
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| Format: | Patent |
| Sprache: | eng ; fre ; ger |
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| Zusammenfassung: | The present invention relates to a process for the preparation of cefadroxil in crystal form, comprising:
a) adding an aqueous solution of cefadroxil to a crystallisation vessel and a titrant to keep a pH in the crystallisation vessel of between 7 to 9; and
b) lowering the pH in the crystallisation vessel to a value of between 5 and 6.5 to obtain a suspension of the ²-lactam compound in crystal form. |
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