Method for identifying compounds modulating adiponectin gene expression

The invention relates to a method for identifying suitable compounds for the treatment and/or prevention of metabolic diseases in which there are altered adiponectin levels, which method uses reporter cell systems containing DNA constructs comprising the adiponectin gene promoter region operatively...

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1. Verfasser: SANTAMARIA NUNEZ, GEMA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to a method for identifying suitable compounds for the treatment and/or prevention of metabolic diseases in which there are altered adiponectin levels, which method uses reporter cell systems containing DNA constructs comprising the adiponectin gene promoter region operatively coupled to a reporter gene and in which the compounds causing an alteration in the reporter gene expression form candidates that are useful in the treatment or prevention of said metabolic diseases.