5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PRASIT, PETPIBOON, PEPPI, LI, YIWEI, STOCK, NICHOLAS, SIMON, HADDACH, MUSTAPHA, MORAN, MARK, ZUNIC, JASMINE, ELEANOR, STEARNS, BRIAN, ANDREW, ROPPE, JEFFREY, ROGER, EVANS, JILLIAN, F, HUTCHINSON, JOHN, H, ARRUDA, JEANNIE, M
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.