Novel amide derivatives as growth hormone secretagogues

Disclosed are the novel compounds as growth hormone secretagogues represented by structural Formula (I), wherein R 1 is, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryl, or substituted or unsubstituted amino, X is -CO- or -SO 2 -, Y is a substituted or unsubstituted group of Formula (II). R 2 is hydrogen, or substituted or unsubstituted alkyl, R 3 is substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, D is substitued or unsubstituted amino, substituted or unsubstituted alkoxy, or substituted or unsubstituted alkylthio, * represents an asymmetric center, and pharmaceutically acceptable salts and individual isomers thereof, which have growth hormone releasing activity in humans or animals.