GSK-3 INHIBITORS

GSK-3 INHIBITORS

The invention relates to urea derivatives of formula (I) as inhibitors of glycogen synthasc kinase 3², GSK-3, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which GSK-3 is involved,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MARTÍN APARICIO, Ester, MEDINA PADILLA, Miguel, PÉREZ PUERTO, María José, CASTRO MORERA, Ana, NAVARRO RICO, María Luisa, ALONSO CASCÓN, Mercedes, FUERTES HUERTA, Ana, MARTÍNEZ GIL, Ana
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention relates to urea derivatives of formula (I) as inhibitors of glycogen synthasc kinase 3², GSK-3, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which GSK-3 is involved, such as Alzheimer's disease or non-insulin dependent diabetes mellitus.