Biodegradable, anionic polymers derived from the aminoacid l-tyrosine

A biodegradable, biocompatible polymer, comprising a combination of monomeric repeating units having structures I and IV wherein R9 is an alkyl, aryl or alkylaryl group with up to 18 carbon atoms having a pendant benzyl carboxylic acid ester group and; R12 is an alkyl, aryl or alkylaryl group with u...

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Bibliographische Detailangaben
Hauptverfasser:	KOHN, JOACHIM, B, BOLIKAL, DURGADAS, KEMNITZER, JOHN E, ERTEL, SYLVIE I, GUAN, SHUIYUN, BRODE, GEORGE L
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	A biodegradable, biocompatible polymer, comprising a combination of monomeric repeating units having structures I and IV wherein R9 is an alkyl, aryl or alkylaryl group with up to 18 carbon atoms having a pendant benzyl carboxylic acid ester group and; R12 is an alkyl, aryl or alkylaryl group with up to 18 carbon atoms having a pendent carboxylic acid ester group selected from the group consisting of straight and branched alkyl and alkylaryl esters containing up to 18 carbon atoms and ester derivatives of biologically and pharmaceutically active compounds covalently bonded to said polymer, provided that said ester group is not a benzyl group or a group that is removed by hydrogenolysis.