3'MODIFIED OLIGONUCLEOTIDES CONTAINING PSEUDOISOCYTOSINE NUCLEOBASE DERIVATIVES AND APPLICATIONS THEREOF AS PRIMERS OR PROBES

Disclosed, among other things, are primers containing certain modified nucleobases in the 3' terminal region of the primers that provide reduced formation of primer-dimers during amplification reactions, and various methods of use thereof.

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Bibliographische Detailangaben
Hauptverfasser: MULLAH, KHAIRUZZAMAN BASHAR, MA, ZHAOCHUN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed, among other things, are primers containing certain modified nucleobases in the 3' terminal region of the primers that provide reduced formation of primer-dimers during amplification reactions, and various methods of use thereof.