DIARYLSULFONE SULFONAMIDES AND USE THEROF

Compounds of Formula 1, or pharmaceutically acceptable salts thereof, are provided: which are modulators of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis.

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Bibliographische Detailangaben
Hauptverfasser: MOLINARI, ALBERT, JOHN, KRISHNAMURTHY, GIRIJA, WOODWORTH, RICHARD, P, WEBB, MICHAEL, BYRON, WELMAKER, GREGORY, SCOTT, SHI, MENGXIAO, MOORE, WILLIAM, JAY, KERN, JEFFERY, CURTIS, WILSON, MATTHEW, ALLAN, GOPALSAMY, ARIAMALA, COMMONS, THOMAS, JOSEPH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Compounds of Formula 1, or pharmaceutically acceptable salts thereof, are provided: which are modulators of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis.