P-CADHERIN ANTIBODIES

The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HEAD, RICHARD DAVID, BOURNER, MAUREEN, JERI, MINTER, RALPH RAYMOND, BAUER, CHRISTOPHER T, JOY, WILLIAM DEAN, BOYLE, MELANIE, MOFFAT, MARK ALLEN, GRIGGS, DAVID WILLIAM, MAZZARELLA, RICHARD ALLEN, THIELE, BARRETT RICHARD, VANARSDALE, TODD LEE, CASPERSON, GERALD FRIES
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.