CRYSTALLINE SQUALAMINE DILACTATE

The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GILBERT, CHARLES, CHELLQUIST, ERIC, LEVITT, ROY, C, DOUBLEDAY, MARY, ZHANG, XUEHAI, MCLANE, MICHAEL, ARMBRUSTER, KYLE
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation