PHOSPHINE TRANSITION METAL COMPLEX, PROCESS FOR PRODUCING THE SAME AND ANTICANCER DRUG CONTAINING THE SAME

There is provided a novel transition metal phosphine complex having excellent anticancer activity. The transition metal phosphine complex is represented by general formula (1): (wherein R 1 s and R 3 s each represent an alkyl group, a cycloalkyl group, an aryl group, an aralkyl group, a pyridyl grou...

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Hauptverfasser: OOHARA, NOBUHIKO, KANEDA, YOSHIROU, KODAMA, HIROAKI, NAKATSUI, KAZUHIRO, OHTO, KEISUKE
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:There is provided a novel transition metal phosphine complex having excellent anticancer activity. The transition metal phosphine complex is represented by general formula (1): (wherein R 1 s and R 3 s each represent an alkyl group, a cycloalkyl group, an aryl group, an aralkyl group, a pyridyl group, or a pyrimidyl group; R 2 s and R 4 s each represent an alkyl group or a cycloalkyl group, provided that each R 1 and each R 2 are not the same group and that each R 3 and each R 4 are not the same group; As each represent a linear alkylene group or a cis-vinylene group; M represents a gold atom, a silver atom, a copper atom, or a platinum atom; and B represents an anionic species).