AZOLYLACYLGUANIDINES AS ß-SECRETASE INHIBITORS
The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit beta-secretase (BACE) and treat beta-amyloid deposits and neurofibrillary tangles.
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| creator | LOVERING, FRANK ELDRIDGE ELLINGBOE, JOHN WATSON MOORE, WILLIAM JAY STOCK, JOSEPH RAYMOND MORRIS, KOI MICHELE MANAS, ERIC STEVEN ZHOU, PING COLE, DEREK CECIL CONDON, JEFFREY SCOTT JENNINGS, LEE DALTON SUKHDEO, MOHANI NIRMALA WU, JUNJUN |
| description | The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit beta-secretase (BACE) and treat beta-amyloid deposits and neurofibrillary tangles. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AZOLYLACYLGUANIDINES AS ß-SECRETASE INHIBITORS |
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