Implants comprising FK506

Implant (A) contains FK506 in chemically bound (covalent or non-covalent) or physically fixed form and optionally at least one other active agent (II). Independent claims are also included for the following: (a) preparation of (A) optionally coated with active agents, and (b) a stent with a polymeri...

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Bibliographische Detailangaben
Hauptverfasser:	KUTTLER, BERND, WNENDT, STEPHAN, LANG, GERHARD, VON OEPEN, RANDOLF
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS
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Beschreibung
Zusammenfassung:	Implant (A) contains FK506 in chemically bound (covalent or non-covalent) or physically fixed form and optionally at least one other active agent (II). Independent claims are also included for the following: (a) preparation of (A) optionally coated with active agents, and (b) a stent with a polymeric surface including, in chemically bound (covalent or non-covalent) or physically fixed form, at least one physiologically and/or pharmaceutically active agent. ACTIVITY : Vasotropic. MECHANISM OF ACTION : None given in the source material. Die Erfindung betrifft Implantate, insbesondere intrakavernöse oder intravaskuläre, vorzugsweise zur Behandlung oder Prophylaxe von koronaren oder peripheren Gefäßverengungen oder -verschlüssen, insbesondere von Verengungen bzw. Stenosen oder Restenosen, vorzugsweise zur Prophylaxe von Restenose, die in chemisch kovalent oder nicht-kovalent gebundener oder physikalisch fixierter Form FK506 enthalten, Verfahren zu deren Herstellung und deren Verwendung.