LEADER SEQUENCES FOR DIRECTING SECRETION OF POLYPEPTIDES AND METHODS FOR PRODUCTION THEREOF

The present invention provides leader sequences that are useful for the production of heterologous secretable polypeptides; heterologous secreted polypeptides; nucleic acid constructs that encode such leader sequences and heterologous secreted polynucleotides; vectors that contain such nucleic acid...

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Bibliographische Detailangaben
Hauptverfasser: BOSCH, ELIZABETH, LINNEMANN, THOMAS, LEE, ERNESTINE, HALENBECK, ROBERT, FORGAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides leader sequences that are useful for the production of heterologous secretable polypeptides; heterologous secreted polypeptides; nucleic acid constructs that encode such leader sequences and heterologous secreted polynucleotides; vectors that contain such nucleic acid constructs; recombinant host cells that contain such nucleic acid constructs; vectors, polypeptides, and methods of making and using such secreted polypeptides with such heterologous leader sequences.