METHOD FOR TESTING SUBSTANCES ON BIOMATRICES

The invention relates to a method for testing one or several substances. According to said method, a tissue equivalent is cultivated, the substance/s is/are made to affect the tissue equivalent, and it is determined whether the effect of the substance/s has resulted in a modification of the tissue e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GOERNE, MARTIN, KAUFMANN, PETER-MATTHIAS
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention relates to a method for testing one or several substances. According to said method, a tissue equivalent is cultivated, the substance/s is/are made to affect the tissue equivalent, and it is determined whether the effect of the substance/s has resulted in a modification of the tissue equivalent and/or the substance/s. The tissue equivalent comprises at least one cell and a porous matrix based on a biologically compatible polymer or polymer mixture. The matrix is provided with pores having a maximum size of 150 μm as well as pores having a minimum size of 300 μm while the degree of porosity is 93 to 98 percent.