RATIONALLY DESIGNED SELECTIVE BINDING POLYMERS

A polymer able to bind a target compound selectively is designed by producing a virtual library of polymerisable monomers, and molecular models of the target compound and one or more potential interferents. The library is screened to identify monomers with substantial differences in strengths of bin...

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Bibliographische Detailangaben
Hauptverfasser: PILETSKA, OLENA VOLODIMIRIVNA, KARIM, KHALKU, LEGGE, COULTON HEATH, SUBRAHMANYAM, SREENATH, PILETSKY, SERGEY ANATOLIYOVICH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A polymer able to bind a target compound selectively is designed by producing a virtual library of polymerisable monomers, and molecular models of the target compound and one or more potential interferents. The library is screened to identify monomers with substantial differences in strengths of binding to (a) target and (b) interferent. Monomers favouring the target may be used to produce polymers for selectively binding the target, for use in separation or analytical processes.