ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS

The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation, cancer and related conditions. The compounds have a general Formula I wherein A1, A2, A3, B, R1, R2, R3 and R4 are defined herein. Accordingl...

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Hauptverfasser:	TEMPEST, Paul A, MASSE, Craig E, TOMLINSON, Susan Ann, ALBRECHT, Brian K, PARAS, Nick A, HODOUS, Brian L, WHITE, Ryan, THAMAN, Maya C, MCGOWAN, David C, PETTUS, Liping H, RZASA, Robert M, CHAFFEE, Stuart C, BUCKNER, William H, BUCHANAN, John L, HABGOOD, Gregory J, FALSEY, James Richard, DIMAURO, Erin F, BELLON, Steven, BEMIS, Jean E, CAO, Guo-giang, DEAK, Holly L, LIU, Gang, XU, Shimin, SMITH, Adrian Leonard, HERBERICH, Bradley J, CEE, Victor J, PATEL, Vinod F, ZHANG, Dawei, KIM, Joseph L, MARTIN, Matthew W, SHAM, Kelvin, GRACEFFA, Russell, TASKER, Andrew, REED, Anthony, HARMANGE, Jean-christophe, CHAKRABARTI, Partha P, DEMORIN, Frenel F, GEUNS-MEYER, Stephanie D, OLIVIERI, Philip R
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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