IMINE COMPOUND

An imine compound represented by the formula: wherein A represents a heterocyclic group; R 1 , R 2 , an R 3 each represent a hydrogen atom, a halogen atom, a C 1-10 alkyl group optionally substituted with an aryl group(s) substituted with a halogen atom (s), a C 3-10 cycloalkyl group, a C 1-6 haloal...

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Hauptverfasser: SEKINE, SHINGO, MORITA, AKI, YOSHIMURA, HIROMITSU, OHTA, HIROSHI, TOKUGAWA, KIMIKO, YOSHINAGA, MITSUKANE, TODA, YOSHIHISA, TOMISHIMA, YASUMITSU, TATSUZUKI, MAKOTO, KAKU, AYAKA, SAITO, SHIUJI, MURAKAMI, TOMOMI, ISHIZAKA, TOMOKO, YOSHIMIZU, TAKAO, YOKOBORI, YUJI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An imine compound represented by the formula: wherein A represents a heterocyclic group; R 1 , R 2 , an R 3 each represent a hydrogen atom, a halogen atom, a C 1-10 alkyl group optionally substituted with an aryl group(s) substituted with a halogen atom (s), a C 3-10 cycloalkyl group, a C 1-6 haloalkyl group, a C 1-10 alkoxy group, etc.; R 4 represents an optionally substituted C 1-10 alkyl, C 2-6 alkenyl, or aryl group; R 5 represents a hydrogen atom, a C 1-10 alkoxy group, a C 1-6 haloalkyl group, an optionally substituted C 1-10 alkyl or C 2-6 alkenyl group, an optionally substituted aryl or heterocyclic group, etc.; W represents -CO-, -CO-CO-, -CO-NH-, -CS-NH-, or -SO 2 -, or a cannabinoid-receptor agonist comprising said imine compound as an active ingredient. The imine compound of the present invention has a cannabinoid-receptor agonist effect, and is useful as a therapeutic or prophylactic drug for pains and autoimmune diseases.