AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS

AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediate...

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Bibliographische Detailangaben
Hauptverfasser: ARGADE, ANKUSH, B, HERRON, DAVID, KENT, TEBBE, ANNE, LOUISE, WILEY, MICHAEL, ROBERT, GOODSON, THEODORE, JUNIOR, YEE, YING, KWONG, LEPORE, SALVATORE, DONATO, MENDEL, DAVID, MASTERS, JOHN, JOSEPH, SMITH, GERALD, FLOYD, MARQUART, ANGELA, LYNN, JOSEPH, SAJAN, RATZ, ANDREW, MICHAEL, MERRITT, LEANDER
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor. An example of a compound of formula (I) is (a).