ANGIOTENSIN-(1-7) ELUTING POLYMER-COATED MEDICAL DEVICE TO REDUCE RESTENOSIS AND IMPROVE ENDOTHELIAL CELL FUNCTION

ANGIOTENSIN-(1-7) ELUTING POLYMER-COATED MEDICAL DEVICE TO REDUCE RESTENOSIS AND IMPROVE ENDOTHELIAL CELL FUNCTION

Medical devices with polymer coatings designed to control the release of angiotensin-(1-7) receptor agonists from medical devices are disclosed. The present application also discloses providing vascular stents with angiotensin-(1-7) receptor agonist-containing controlled-release coatings. Methods fo...

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Bibliographische Detailangaben
Hauptverfasser: TIJSMA, EDZE, JAN, DRIESSEN-LEVELS, ANITA, HENDRIKS, MARC
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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Beschreibung
Zusammenfassung:Medical devices with polymer coatings designed to control the release of angiotensin-(1-7) receptor agonists from medical devices are disclosed. The present application also discloses providing vascular stents with angiotensin-(1-7) receptor agonist-containing controlled-release coatings. Methods for treating or inhibiting post-stent implantation restenosis as well as improving vascular endothelial function in patients are also provided.