HCV NON-STRUCTURAL PROTEIN MUTANTS AND USES THEREOF

Modified HCV multiple epitope fusion antigens (MEFAs) are described. The proteins include modified sequences such that proteolytic cleavage of the MEFAs by HCV NS3 protease is inhibited. HCV immunoassays including the modified MEFAs are also described.

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Bibliographische Detailangaben
Hauptverfasser: MEDINA-SELBY, ANGELICA, COIT, DORIS, LIN, SANSAN, CHIEN, DAVID Y, HU, CELINE YUAN-HWEI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Modified HCV multiple epitope fusion antigens (MEFAs) are described. The proteins include modified sequences such that proteolytic cleavage of the MEFAs by HCV NS3 protease is inhibited. HCV immunoassays including the modified MEFAs are also described.