POLYSACCHARIDE-BASED POLYMER TISSUE ADHESIVE FOR MEDICAL USE

Method of forming tissue adhesives by reacting an oxidized polysaccharide with a water-dispersible multi-arm polyether amine, wherein at least three of the arms are terminated by primary amine groups, are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topi...

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Bibliographische Detailangaben
Hauptverfasser: KODOKIAN, GEORGE, K, ARTHUR, SAMUEL, DAVID
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Method of forming tissue adhesives by reacting an oxidized polysaccharide with a water-dispersible multi-arm polyether amine, wherein at least three of the arms are terminated by primary amine groups, are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; drug delivery; anti-adhesive applications; and as a bulking agent to treat urinary incontinence are described.