NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM

The present invention is directed to a compounds, methods and compositions for making the compounds and methods of treating a variety of diseases and disease states including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expressi...

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Hauptverfasser: PADAKANTI, SRIVINAS, PAL, MANOJIT, YELESWARAPU, KOTESWAR, RAO, KHANNA, ISH, KUMAR, PILLARISETTI, SIVARAM, ALEXANDER, CHRISTOPHER, W, BARANGE, DEEPAK, KALLEDA, SRINIVAS, IQBAL, JAVED, KUMAR SWAMY, NALIVELA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention is directed to a compounds, methods and compositions for making the compounds and methods of treating a variety of diseases and disease states including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan, comprising the administration of new heterocyclic compounds, particularly substituted pyrimidines. The present invention is directed to novel compounds represented by the general formula: