METHOD FOR PREPARING 5-[4-(2-HYDROXY-PROPYL)-3,5-DIOXO-4,5-DIHYDRO-3H[1,2,4]TRIAZIN-2-YL]-BENZAMIDE DERIVATIVES BY DEPROTECTING THE HYDROXYL-PROTECTED PRECURSERS

METHOD FOR PREPARING 5-[4-(2-HYDROXY-PROPYL)-3,5-DIOXO-4,5-DIHYDRO-3H[1,2,4]TRIAZIN-2-YL]-BENZAMIDE DERIVATIVES BY DEPROTECTING THE HYDROXYL-PROTECTED PRECURSERS

The present invention relates to the methods for preparing compounds of the formula I: or the pharmaceutically acceptable salts thereof, wherein R1, R2, R4, R10, and R11 have any of the values defined in the specification. The compounds of the present invention are useful in the treatment of disease...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: LI, ZHENGONG, B
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to the methods for preparing compounds of the formula I: or the pharmaceutically acceptable salts thereof, wherein R1, R2, R4, R10, and R11 have any of the values defined in the specification. The compounds of the present invention are useful in the treatment of diseases, including inflammatory diseases such as rheumatoid arthritis.