RSF1010 DERIVATIVE MOB-DEFICIENT PLASMID CONTAINING NO ANTIBIOTIC RESISTANCE GENE, BACTERIUM COMPRISING THE PLASMID AND METHOD FOR PRODUCING USEFUL METABOLITES

A Mob- plasmid having a RSF1010 replicon, comprising a gene coding for Rep protein and said plasmid has been modified to inactivate gene related to mobilization ability. The present invention also describes a bacterium having an ability to produce useful metabolites, comprising the plasmid and said...

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Hauptverfasser: GULEVICH, ANDREY YURIEVICH, MIRONOV, ALEKSANDR, SERGEEVICH, KATASHKINA, JOANNA YOSIFOVNA, SKOROKHODOVA, ALEKSANDRA YURIEVNA, ERRAIS, LOPES, LUBOV, ZIMENKOV, DANILA VADIMOVICH, MASHKO, SERGEI, VLADIMIROVICH, BIRYUKOVA, IRINA, VLADIMIROVNA
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creator GULEVICH, ANDREY YURIEVICH
MIRONOV, ALEKSANDR, SERGEEVICH
KATASHKINA, JOANNA YOSIFOVNA
SKOROKHODOVA, ALEKSANDRA YURIEVNA
ERRAIS, LOPES, LUBOV
ZIMENKOV, DANILA VADIMOVICH
MASHKO, SERGEI, VLADIMIROVICH
BIRYUKOVA, IRINA, VLADIMIROVNA
description A Mob- plasmid having a RSF1010 replicon, comprising a gene coding for Rep protein and said plasmid has been modified to inactivate gene related to mobilization ability. The present invention also describes a bacterium having an ability to produce useful metabolites, comprising the plasmid and said bacterium lack active thymidylate synthase coded by thyA gene and thymidine kinase coded by tdk gene, and a method for producing useful metabolites, such as native or recombinant proteins, enzymes, L-amino acids, nucleosides and nucleotides, vitamins, using the bacterium.
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The present invention also describes a bacterium having an ability to produce useful metabolites, comprising the plasmid and said bacterium lack active thymidylate synthase coded by thyA gene and thymidine kinase coded by tdk gene, and a method for producing useful metabolites, such as native or recombinant proteins, enzymes, L-amino acids, nucleosides and nucleotides, vitamins, using the bacterium.</abstract><oa>free_for_read</oa></addata></record>
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title RSF1010 DERIVATIVE MOB-DEFICIENT PLASMID CONTAINING NO ANTIBIOTIC RESISTANCE GENE, BACTERIUM COMPRISING THE PLASMID AND METHOD FOR PRODUCING USEFUL METABOLITES
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