CHIMERIC HUMAN GROWTH HORMONE DERIVED FROM THE PLACENTA AND PITUITARY ISOFORM AND PROCESSES FOR OBTAINING SAID CHIMERA

A way to increase the production of recombinant polypeptides by combining pieces of several different isoforms of a given gene to make a chimeric isoform of the gene (using a chimeric gene can increase the production of polypeptide over 25%), or by inserting several copies of the coding region in ta...

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Bibliographische Detailangaben
Hauptverfasser:	NIPHADKAR, PRABHAKAR, MILIND, BORBHUIYA, AHMED MONSUR, MISHRA, SHRIKANT, KHARE, GANESH ARUNA, MAITI, DIPANWITA, RAO, SRINIVAS, LAXMI
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A way to increase the production of recombinant polypeptides by combining pieces of several different isoforms of a given gene to make a chimeric isoform of the gene (using a chimeric gene can increase the production of polypeptide over 25%), or by inserting several copies of the coding region in tandem into a transformation vector (e.g., plasmids carrying multiple copies of the chimera of SEQ ID NO: 3 increased production 107%).