PHARMACEUTICAL COMPOSITIONS COMPRISING NEP-INHIBITORS, INHIBITORS OF THE ENDOGENOUS ENDOTHELIN PRODUCING SYSTEM AND PDE V INHIBITORS

PHARMACEUTICAL COMPOSITIONS COMPRISING NEP-INHIBITORS, INHIBITORS OF THE ENDOGENOUS ENDOTHELIN PRODUCING SYSTEM AND PDE V INHIBITORS

A novel combination therapy is described for the prophylaxis and/or treatment of sexual dysfunction and/or cardiovascular diseases in mammals and humans, by administering a synergistic combination of at least one inhibitor of neutral endopeptidase, at least one inhibitor of the endogenous endothelin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZIEGLER, DIETER, STRAUB, MATTHIAS, WESKE, MICHAEL, WITTE, KLAUS, HOELTJE, DAGMAR
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A novel combination therapy is described for the prophylaxis and/or treatment of sexual dysfunction and/or cardiovascular diseases in mammals and humans, by administering a synergistic combination of at least one inhibitor of neutral endopeptidase, at least one inhibitor of the endogenous endothelin producing system and at least one inhibitor of phosphodiesterase 5.